oral liquid dosage
helping the medicine go down
Oral liquid dosage forms are liquid-state pharmaceutical preparations for oral administration, often used when patients have difficulty swallowing solid dosage forms like tablets or capsules or when dose flexibility is necessary. Oral liquid dosage forms are available in various forms such as solutions, suspensions, emulsions, and syrups.
Appropriate excipients may be added to oral liquid dosage forms to improve stability, palatability, and appearance, making them more acceptable to patients, especially children. Oral liquid dosage forms may require refrigeration or special storage conditions depending on their formulation, and they usually have a shorter shelf life compared to solid dosage forms.
Ashland offers:
- natrosol™ 250 m pharm hydroxyethylcellulose that is a thickener/viscosity modifier easily dispersed in cold or hot water to give solutions of varying viscosities and desired properties, although it is insoluble in organic solvents. It is used in solutions to control rheology, stable over a broad pH range, and suitable to match typical viscosity profiles of pharmaceutical syrups
- CAVASOL* and CAVAMAX* cyclodextrins that improve solubility of poorly soluble compounds; the same mechanism makes these excipients capable of masking unpleasant taste/odor and stabilizing APIs that are prone to degradation.
- plasdone™ K-12 povidone that is used to enhance the solubility of active pharmaceutical ingredients, increase bioavailability, and inhibit recrystallization of ingredients in pharmaceutical syrups.
- blanose™ sodium carboxymethylcellulose (CMC) that are used as thickeners and suspending aids for syrups and suspensions
*Registered trademark owned by Wacker Chemie AG. Ashland acts as a worldwide distributor for Wacker.
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CAVAMAX™ native cyclodextrins
The molecular structure of cyclodextrins creates a bucket-like cavity that can complex with molecules or functional groups on molecules to improve solubility of poorly soluble compounds. The same mechanism makes these excipients capable of masking unpleasant taste/odor and stabilizing drugs that are prone to degradation. The number of glucose units in the ring determines the internal diameter of the cavity and its volume, as the height of the cyc...
natrosol™ 250 pharm hydroxyethylcellulose
Natrosol™ pharm HEC grades are non-ionic, water-soluble polymer widely used in pharmaceutical formulations. This product is easily dispersed in cold or hot water to give solutions of varying viscosities and desired properties, though it is insoluble in organic solvents. It is used in solutions and gels to control rheology, in emulsions for high-salt tolerance and surfactant compatibility, and in modified-release matrix tablets where high-vi...
CAVAMAX® W6 Pharma
CAVAMAX® , CAVASOL® and cavitron™ cyclodextrins have the unique ability to act as molecular containers by entrapping guest molecules in their internal cavities. The resulting inclusion complexes are used in a number of applications in pharmaceutical formulations. For example, cyclodextrins increase water solubility of poorly soluble drugs to improve bioavailability, taste mask bitter actives for use in chewable and orally disintegrating tablet ap...
CAVAMAX® W8 Pharma
CAVAMAX® , CAVASOL® and cavitron™ cyclodextrins have the unique ability to act as molecular containers by entrapping guest molecules in their internal cavities. The resulting inclusion complexes are used in a number of applications in pharmaceutical formulations. For example, cyclodextrins increase water solubility of poorly soluble drugs to improve bioavailability, taste mask bitter actives for use in chewable and orally disintegrating tablet ap...
plasdone™ povidone
Ashland offers a comprehensive range of Plasdone™ povidones (PVP). Plasdone™ povidones are a family of water-soluble polymers based on N-vinylpyrrolidone that combine a unique set of properties for application in a wide variety of dosage forms. Plasdone™ povidones are commonly used as binders for the development of tablet formulations, whether manufactured by wet granulation, dry granulation or direct compression. Plasdone&trade...
plasdone™ k-17 povidone
Plasdone™ povidones are a family of water-soluble polymers based on N-vinylpyrrolidone that combine a unique set of properties for application in a wide variety of dosage forms. Plasdone ™ povidones are commonly used as binders for the development of tablet formulations, whether manufactured by wet granulation, dry granulation, or direct compression. Plasdone ™ K polymers are used in solid dispersion formulations to enhance the solubility of act...
plasdone™ k-12 povidone
Plasdone™ povidones are a family of water-soluble polymers based on N-vinylpyrrolidone that combine a unique set of properties for application in a wide variety of dosage forms. Plasdone™ povidones are commonly used as binders for the development of tablet formulations, whether manufactured by wet granulation, dry granulation, or direct compression. Plasdone™ K polymers are used in solid dispersion formulations to enhance the solubility of active...
natrosol™ 250 g pharm hydroxyethylcellulose
Hydroxyethylcellulose (HEC) is a non-ionic, water-soluble polymer widely used in pharmaceutical formulations.
natrosol™ 250 l pharm hydroxyethylcellulose
Hydroxyethylcellulose (HEC) is a non-ionic, water-soluble polymer widely used in pharmaceutical formulations.
cavitron™ hydroxypropyl-ß- cyclodextrins (HPBCD)
The molecular structure of cyclodextrins creates a bucket-like cavity that can function to complex with molecules or functional groups on molecules. The substitution of hydroxyl groups on native cyclodextrins to make hydroxypropyl-ß- cyclodextrins (HPBCD) significantly enhances their solubility and makes them more suitable for drug solubilization. This mechanism makes the cavitron™ HPBCDs capable of masking unpleasant taste/odor and s...
CAVASOL® W8 HP Pharma
CAVAMAX® , CAVASOL® and cavitron™ cyclodextrins have the unique ability to act as molecular containers by entrapping guest molecules in their internal cavities. The resulting inclusion complexes are used in a number of applications in pharmaceutical formulations. For example, cyclodextrins increase water solubility of poorly soluble drugs to improve bioavailability, taste mask bitter actives for use in chewable and orally disintegrating tablet ap...
CAVASOL® W7 HP Pharma
CAVAMAX® , CAVASOL® and cavitron™ cyclodextrins have the unique ability to act as molecular containers by entrapping guest molecules in their internal cavities. The resulting inclusion complexes are used in a number of applications in pharmaceutical formulations. For example, cyclodextrins increase water solubility of poorly soluble drugs to improve bioavailability, taste mask bitter actives for use in chewable and orally disintegrating tablet ap...
natrosol™ 250 hhx pharm hydroxyethylcellulose
Hydroxyethylcellulose (HEC) is a non-ionic, water-soluble polymer widely used in pharmaceutical formulations.
natrosol™ 250 h pharm hydroxyethylcellulose
Hydroxyethylcellulose (HEC) is a non-ionic, water-soluble polymer widely used in pharmaceutical formulations.
natrosol™ 250 hx pharm hydroxyethylcellulose
Hydroxyethylcellulose (HEC) is a non-ionic, water-soluble polymer widely used in pharmaceutical formulations.
natrosol™ 250 m pharm hydroxyethylcellulose
Hydroxyethylcellulose (HEC) is a non-ionic, water-soluble polymer widely used in pharmaceutical formulations.
blanose™ sodium carboxymethylcellulose
Since its commercial introduction in the United States in 1946, Aqualon™ (Blanose) sodium carboxymethylcellulose (CMC) has found use in an ever-increasing number of applications. The many important functions provided by this polymer make it a preferred thickener, suspending aid, stabilizer, binder and film-former in a growing variety of applications. The wide range of viscosity and substitution types available for the highly purified grades...
blanose™ 7hf ph sodium carboxymethylcellulose
Blanose™ CMC is an anionic, water-soluble polymer. A variety of CMC grades are available with varying degrees of substitution, viscosities and particle sizes.
blanose™ 7lf ph sodium carboxymethylcellulose
Blanose™ CMC is an anionic, water-soluble polymer. A variety of CMC grades are available, with varying degrees of substitution, viscosities and particle sizes.
blanose™ 7h4xf ph sodium carboxymethylcellulose
Blanose™ CMC is an anionic, water-soluble polymer. A variety of CMC grades are available, with varying degrees of substitution, viscosities and particle sizes.
blanose™ 7hxf ph sodium carboxymethylcellulose
Blanose™ CMC is an anionic, water-soluble polymer. A variety of CMC grades are available, with varying degrees of substitution, viscosities and particle sizes.
blanose™ 7lp ep sodium carboxymethylcellulose
Blanose™ CMC is an anionic, water-soluble polymer. A variety of CMC grades are available, with varying degrees of substitution, viscosities and particle sizes.
blanose™ 7mf ph sodium carboxymethylcellulose
Blanose™ CMC is an anionic, water-soluble polymer. A variety of CMC grades are available, with varying degrees of substitution, viscosities and particle sizes.
blanose™ 7h3sxf ph sodium carboxymethylcellulose
Blanose™ CMC is an anionic, water-soluble polymer. A variety of CMC grades are available, with varying degrees of substitution, viscosities and particle sizes.
CAVASOL* HPBCD
The molecular structure of cyclodextrins creates a bucket-like cavity that can function to complex with molecules or functional groups on molecules. The substitution of hydroxyl groups on native cyclodextrins to make hydroxypropyl-ß- cyclodextrins (HPBCD) significantly enhances their solubility and makes them more suitable for drug solubilization. This mechanism makes the cavitron™ HPBCDs capable of masking unpleasant taste/odor and s...