klucel fusion™ hpc
Ashland introduces klucel fusion™ hpc - the only immediate release tablet binder designed for melt granulation.
The leading high performance tablet binder just got better. Klucel Fusion™ HPC is a new hydroxypropyl cellulose (HPC) polymer that is expressly designed to optimize performance in twin screw melt granulation (TSMG).
Klucel Fusion™ HPC offers the stellar tablet binding performance you’ve come to expect from Klucel™ HPC at a significantly lower melt processing temperature.
features
- low extrusion process temperatures (50°C- 80°C)
- lower melt viscosity that enables trouble-free extrusion
- improved tabletability at a low binder level of 5%
benefits
- less thermal and shear-induced degradation of the API
- excellent choice for melt granulating of thermolabile and moisture-sensitive drugs
- enables melt granulation that is considered to be a, simpler, cheaper, faster, and more consistent drug manufacturing process than wet granulation
- improved environmental impact via reduced water usage and potential energy savings
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